Subjects with the T allele exhibited a significantly decreased risk of schizophrenia. We found that the S100B rs1800614 T allele is a protective factor for schizophrenia in the Han Chinese population. Multifactor dimensionality reduction (MDR) analysis was performed to evaluate the multifactor risk of genetic susceptibility. We examined rs1800614 genotype distribution in 908 schizophrenia patients and 1036 healthy controls. The aim of this study was to evaluate the effect of S100B rs1800614 on the risk of schizophrenia in Han Chinese.

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